Sigma-1 receptor regulates mitophagy in dopaminergic neurons and contributes to dopaminergic protection
Mingmei Wang, Chunlei Wan, Tao He, Chaojun Han, Kailian Zhu, John L. Waddington, Xuechu Zhen
Topics & Concepts
MitophagyPINK1ParkinMPTPSubstantia nigraDopaminergicCell biologyAutophagyChemistryMitochondrionAgonistHydroxydopaminePars compactaBiologyReceptorDopamineEndocrinologyInternal medicineBiochemistryParkinson's diseaseMedicineApoptosisDiseasePharmacological Receptor Mechanisms and EffectsTryptophan and brain disordersNeuroscience and Neuropharmacology Research