RP1, a RAGE antagonist peptide, can improve memory impairment and reduce Aβ plaque load in the APP/PS1 mouse model of Alzheimer's disease
Yiyun Huang, Nian Fang, Huiru Luo, Feng Gao, Yao Zou, Lili Zhou, Qing-Ping Zeng, Shi-song Fang, Fei Xiao, Qing Zheng
Topics & Concepts
Rage (emotion)NeuroprotectionGlycationAntagonistDiseaseAmyloid precursor proteinReceptorPeptideRNACell biologyMedicineBiologyCancer researchGeneAlzheimer's diseasePharmacologyNeuroscienceInternal medicineBiochemistryAlzheimer's disease research and treatmentsAdvanced Glycation End Products researchNatural Antidiabetic Agents Studies