“Double hit” strategy: Removal of sialic acid from the dendritic cell surface and loading with CD44+/CD24-/low cell lysate inhibits tumor growth and metastasis by targeting breast cancer stem cells
Eda Açıkgöz, Fahriye Düzağaç, Ümmü Güven, Gürkan Yiğittürk, Timur Köse, Gülperi Öktem
Topics & Concepts
CD44Dendritic cellCD80CD86Cancer stem cellCancer researchBiologyCell biologyAntigenStem cellT cellCD40Immune systemImmunologyCellCytotoxic T cellIn vitroBiochemistryGeneticsImmunotherapy and Immune ResponsesCancer Cells and MetastasisCancer Research and Treatments