Hirudin ameliorates diabetic nephropathy by inhibiting Gsdmd-mediated pyroptosis
Jiarui Han, Zhenkui Zuo, Xiujie Shi, Yage Zhang, Zining Peng, Yufeng Xing, Xinxin Pang
Topics & Concepts
PyroptosisHirudinPharmacologyMedicineNephropathyDiabetic nephropathyStreptozotocinKidneyIn vivoIn vitroChemistryDiabetes mellitusInternal medicineInflammasomeEndocrinologyBiologyInflammationBiochemistryThrombinPlateletBiotechnologyInflammasome and immune disordersRenal Diseases and GlomerulopathiesNeutrophil, Myeloperoxidase and Oxidative Mechanisms