The Phosphatase Bph and Peptidyl-Prolyl Isomerase PrsA Are Required for Gelatinase Expression and Activity in Enterococcus faecalis
Julia L. E. Willett, Ethan B. Robertson, Gary M. Dunny
Abstract
In Enterococcus faecalis , gelatinase (GelE) is a virulence factor that is also important for biofilm formation and interactions with other microbes as well as the host immune system. The long-standing model for GelE production is that the Fsr quorum sensing system positively regulates expression of gelE .
Topics & Concepts
Enterococcus faecalisGelatinaseBiologyMicrobiologyBiofilmQuorum sensingVirulenceVirulence factorBacteriaGeneEscherichia coliBiochemistryEnzymeGeneticsAntimicrobial Resistance in StaphylococcusBacterial biofilms and quorum sensingStreptococcal Infections and Treatments