Prussian blue nano-enzyme-assisted photodynamic therapy effectively eradicates MRSA infection in diabetic mouse skin wounds
Aidi Tong, Chunyi Tong, Jialong Fan, Jingyi Shen, Caiyun Yin, Zhou Wu, Jiansong Zhang, Bin Liu
Abstract
In the constructed CPB-Ce6 NPs, Ce6 killed MRSA by generating 1 O 2 , CPB NPs used CAT activity to generate O 2 and alleviate hypoxia, and Ce6 used O 2 to enhance PDT. CPB-Ce6 NPs accelerated wound healing in diabetic mice infected with MRSA .
Topics & Concepts
Photodynamic therapyPrussian blueChemistryEnzymeMedicineMicrobiologyBiologyBiochemistryElectrodePhysical chemistryOrganic chemistryElectrochemistryNanoplatforms for cancer theranosticsPhotodynamic Therapy Research StudiesLaser Applications in Dentistry and Medicine