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Discovery and structural optimization of 3-O-β-chacotriosyl oleanane-type triterpenoids as potent entry inhibitors of SARS-CoV-2 virus infections

Hui Li, Chen Cheng, Sumei Li, Yan Wu, Zhihao Liu, Mingjian Liu, Jianxin Chen, Qiuyu Zhong, Xuesha Zhang, Shuwen Liu, Gaopeng Song

2021European Journal of Medicinal Chemistry24 citationsDOIOpen Access PDF

Topics & Concepts

VirusChemistryCoronavirusVirologyVero cellViral entryPharmacologyMicrobiologyCoronavirus disease 2019 (COVID-19)BiologyViral replicationInfectious disease (medical specialty)MedicineDiseasePathologyPharmacological Effects of Natural CompoundsEssential Oils and Antimicrobial Activity
Discovery and structural optimization of 3-O-β-chacotriosyl oleanane-type triterpenoids as potent entry inhibitors of SARS-CoV-2 virus infections | Litcius