Prostate cancer-derived exosomes promote osteoblast differentiation and activity through phospholipase D2

Mathieu Borel, Giovanna Lollo, David Magne, René Buchet, Leyre Brizuela, Saïda Mebarek

2020Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease54 citationsDOI Open Access PDF

Topics & Concepts

MicrovesiclesPLD2ExosomeCancer researchOsteoblastBone metastasisMetastasisChemistryCell biologyPhospholipase DTumor microenvironmentPhosphatidic acidBiologyCancerInternal medicineMedicineSignal transductionBiochemistrymicroRNAIn vitroMembranePhospholipidGeneTumor cellsExtracellular vesicles in diseaseMicroRNA in disease regulationGenital Health and Disease