Recombinant adenovirus expressing the fusion protein PD1PVR improves CD8+ T cell-mediated antitumor efficacy with long-term tumor-specific immune surveillance in hepatocellular carcinoma
Hailin Zhang, Yonghui Zhang, Jie Dong, Shuguang Zuo, Gang Meng, Junhua Wu, Jiwu Wei
Topics & Concepts
Hepatocellular carcinomaCancer researchImmune systemImmunotherapyFusion proteinCD8MedicineRecombinant DNAImmune surveillanceImmunologyBiologyOncologyGeneBiochemistryVirus-based gene therapy researchCancer Research and TreatmentsImmunotherapy and Immune Responses