Serine-threonine Kinase Receptor-Associated Protein is a Critical Mediator of APC Mutation–Induced Intestinal Tumorigenesis Through a Feed-Forward Mechanism
Trung Vu, Arunima Datta, Carolyn E. Banister, Lin Jin, Guandou Yuan, Temesgen Samuel, Sejong Bae, Isam-Eldin Eltoum, Upender Manne, Bixiang Zhang, Robert S. Welner, Kasturi Mitra, Phillip Buckhaults, Pran K. Datta
Topics & Concepts
Wnt signaling pathwayMolecular biologyCarcinogenesisKinaseKnockout mouseCancer researchChemistryColorectal cancerBiologySignal transductionReceptorCell biologyGeneGeneticsCancerWnt/β-catenin signaling in development and cancerCancer Cells and MetastasisGenetic factors in colorectal cancer