The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery
Kiren Baines, Kazuaki Yoshioka, Yoh Takuwa, Jon D. Lane
Abstract
; GFP, green fluorescent protein; HIP1R, huntingtin interacting protein 1 related; MEF, mouse embryo fibroblast; PIK3C2A, phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; SILAC, stable isotope labelling with amino acids in culture; SQSTM1, sequestosome 1; STRING, search tool for the retrieval of interacting genes/proteins.
Topics & Concepts
ClathrinAutophagyInteractomeAutophagosomeATG5Cell biologySignal transducing adaptor proteinChemistryBiologyEndocytosisSignal transductionBiochemistryReceptorGeneApoptosisCellular transport and secretionAutophagy in Disease and TherapyCalcium signaling and nucleotide metabolism