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Fabrication of polyvinyl pyrrolidone-K90/Eudragit RL100-based dissolving microneedle patches loaded with alpha-arbutin and resveratrol for skin depigmentation

Nway Nway Aung, Supusson Pengnam, Tanasait Ngawhirunpat, Theerasak Rojanarata, Prasopchai Patrojanasophon, Praneet Opanasopit, Boonnada Pamornpathomkul

2023Biomaterials Science23 citationsDOIOpen Access PDF

Abstract

< 0.05). Moreover, application of the patches for 24 h was not found to affect skin hydration, transepidermal water loss, or skin elasticity. Therefore, AA/Res-loaded DMN patches could offer a promising approach for the effective local delivery of cosmetic agents for skin depigmentation.

Topics & Concepts

ChemistryDepigmentationIrritationErythemaIn vivoPharmacologyTransepidermal water lossBiophysicsBiomedical engineeringDermatologyStratum corneumMedicineImmunologyPathologyBiologyBiotechnologyAdvancements in Transdermal Drug DeliveryDermatology and Skin DiseasesBee Products Chemical Analysis
Fabrication of polyvinyl pyrrolidone-K90/Eudragit RL100-based dissolving microneedle patches loaded with alpha-arbutin and resveratrol for skin depigmentation | Litcius