Amoebic Liver Abscess: Potential Application of New Diagnostic Techniques for an Old Pathogen
Federica Portunato, Claudia Bartalucci, Antonio Vena, Daniele Roberto Giacobbe, Elisa Porcile, Paolo Montanelli, Nataniele Piol, Monica Centanaro, Enzo Andorno, Matteo Bassetti
Abstract
Amoebic liver abscess is a severe and potentially life-threatening infection requiring prompt diagnosis and early targeted treatment. Diagnosis is challenging because conventional diagnostic methods such as light microscopy and serology are often unreliable. Molecular techniques have emerged as an additional diagnostic tool, suddenly becoming the new diagnostic reference standard. More recently, commercial multiplex PCR panels, including FilmArray, have been introduced, which permit the simultaneous detection of several enteric pathogens including Entamoeba histolytica in stool samples. We report a case of an amoebic liver abscess promptly diagnosed by FilmArray gastrointestinal panel performed on liver drainage fluid.