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Recent developments of human monocarboxylate transporter (hMCT) inhibitors as anticancer agents

Puhua Wu, Yan Zhou, Yizhen Guo, Shaolin Zhang, Kin Yip Tam

2021Drug Discovery Today18 citationsDOI

Topics & Concepts

EffluxTransporterCytosolGlycolysisBiochemistryMonocarboxylate transporterChemistrySmall moleculeIntracellularWarburg effectAnaerobic glycolysisCancer cellComputational biologyBiologyCancerEnzymeGeneGeneticsCancer, Hypoxia, and MetabolismPeroxisome Proliferator-Activated ReceptorsDrug Transport and Resistance Mechanisms
Recent developments of human monocarboxylate transporter (hMCT) inhibitors as anticancer agents | Litcius