Abnormal neocortex arealization and Sotos-like syndrome–associated behavior in <i>Setd2</i> mutant mice
Lichao Xu, Yue Zheng, Xuejing Li, Andi Wang, Dawei Huo, Qinglan Li, Shikang Wang, Zhiyuan Luo, Ying Liu, Fuqiang Xu, Xudong Wu, Min Wu, Yan Zhou
Abstract
heterozygous mice. Together, our study emphasizes epigenetic mechanisms underlying cortical arealization and pathogenesis of the Sotos-like syndrome.
Topics & Concepts
NeocortexSotos syndromeMutantBiologyGeneticsNeuroscienceGeneGenetic Syndromes and ImprintingEpigenetics and DNA MethylationRNA Research and Splicing