The catalytic influence of phosphotungstic acid-functionalized Fe<sub>3</sub>O<sub>4</sub> MNPs blended with TiO<sub>2</sub> on the synthesis of novel spiro-acridines and the evaluation of their medicinal potential through molecular docking studies
Shweta Potdar, Nikita Pal, Pratibha Sharma, Ashok Kumar
Abstract
This manuscript describes an effective and rapid three-component synthesis of a novel series of spiro-acridine derivatives by integrating the pharmacologically dynamic hydantoin–phenytoin as the prime synthetic equivalent.
Topics & Concepts
CatalysisPhosphotungstic acidMaterials scienceAcridineSolventNanoparticleProton NMRNuclear chemistryChemistryChemical engineeringNanotechnologyOrganic chemistryEngineeringMulticomponent Synthesis of HeterocyclesSynthesis and biological activityClick Chemistry and Applications