Poppers, by Inducing HHV-8 Virion Production, Can Act as a Promoter for HHV-8 Transmission in Men Who Have Sex With Men
Aude Jary, Adélie Gothland, Romain Palich, Valentin Leducq, Gentiane Monsel, Sébastien Imbert, Luminita Schneider, Anne Simon, Jean‐Philippe Spano, Christine Katlama, Islam Amine Larabi, Jean‐Claude Alvarez, Vincent Cálvez, Anne‐Geneviève Marcelin
Abstract
Environmental factors were reported to increase the risk of human herpesvirus 8 (HHV-8) transmission. In a population of men who have sex with men (MSM), we found evidence that chemsex was associated with human herpesvirus 8 seropositivity in vivo and that poppers induced HHV-8 virion production in vitro. Our finding may explain the higher HHV-8 transmission in MSM.
Topics & Concepts
Men who have sex with menTransmission (telecommunications)MedicineHuman herpesvirusHuman herpesvirus 6VirologyPopulationHuman immunodeficiency virus (HIV)Environmental healthHerpesviridaeViral diseaseTelecommunicationsSyphilisComputer scienceCytomegalovirus and herpesvirus researchViral-associated cancers and disordersPolyomavirus and related diseases