Synthesis, anticancer evaluation and molecular docking studies of new heterocycles linked to sulfonamide moiety as novel human topoisomerase types I and II poisons
Ahmed H. Halawa, Walid E. Elgammal, Saber M. Hassan, Ahmed Hassan, Hesham S. Nassar, Hassan Y. Ebrahim, Ahmed B. M. Mehany, Ahmed M. El‐Agrody
Topics & Concepts
ChemistryMoietyDocking (animal)StereochemistryTopoisomeraseDNACombinatorial chemistryBiochemistryMedicineNursingCancer therapeutics and mechanismsSynthesis and Biological EvaluationEnzyme function and inhibition