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Synthesis, anticancer evaluation and molecular docking studies of new heterocycles linked to sulfonamide moiety as novel human topoisomerase types I and II poisons

Ahmed H. Halawa, Walid E. Elgammal, Saber M. Hassan, Ahmed Hassan, Hesham S. Nassar, Hassan Y. Ebrahim, Ahmed B. M. Mehany, Ahmed M. El‐Agrody

2020Bioorganic Chemistry43 citationsDOI

Topics & Concepts

ChemistryMoietyDocking (animal)StereochemistryTopoisomeraseDNACombinatorial chemistryBiochemistryMedicineNursingCancer therapeutics and mechanismsSynthesis and Biological EvaluationEnzyme function and inhibition
Synthesis, anticancer evaluation and molecular docking studies of new heterocycles linked to sulfonamide moiety as novel human topoisomerase types I and II poisons | Litcius