The Role of Salivary C-Reactive Protein in Systemic and Oral Disorders: A Systematic Review
Mahsa Babaei, Saeid Rezaei, Shadi Saghafi Khadem, Iman Shirinbak, Samira Basir Shabestari
Abstract
Background: Blood sampling is expensive, time-consuming, invasive, and requires technical facilities, which can be replaced by more convenient samples such as saliva. C-reactive protein (CRP) is a widely used biomarker in the management of many disorders and plasma CRP (pCRP) is suggested to be replaced by salivary CRP (sCRP). This study aimed to systematically review all available literature on the sCRP levels in systemic and oral disorders and how sCRP and pCRP levels correlate among these patients and healthy individuals.
Topics & Concepts
SalivaBiomarkerMedicineC-reactive proteinScopusBioinformaticsInternal medicineMEDLINEInflammationBiologyBiochemistrySalivary Gland Disorders and FunctionsOral microbiology and periodontitis researchStreptococcal Infections and Treatments