Human Monkeypox in People With HIV: Transmission, Clinical Features, and Outcome
María Jesús Vivancos, Matilde Sánchez‐Conde, Mario Rodríguez-Domínguez, Pablo Fernández‐González, Laura Martínez García, Emilio Garcia‐Mouronte, Javier Martínez‐Sanz, Ana Moreno‐Zamora, José L. Casado, Raquel Ron, Juan Carlos Galán, Marı́a Jesús Pérez-Elı́as, Santiago Moreno
Abstract
We describe the first 25 persons with HIV diagnosed with human monkeypox virus (MPXV) in our hospital in an ongoing outbreak in Spain. Proctitis was the predominant finding in 52%, and MPXV DNA was detected in rectal swabs from 90%. Proctitis and demonstration of MPXV in rectal swabs support the sexual transmission of MPXV.
Topics & Concepts
MonkeypoxMedicineOutbreakTransmission (telecommunications)VirologyProctitisViral sheddingMen who have sex with menHuman immunodeficiency virus (HIV)VirusInternal medicineDiseaseVacciniaBiologyUlcerative colitisBiochemistryEngineeringGeneElectrical engineeringSyphilisRecombinant DNAPoxvirus research and outbreaksHerpesvirus Infections and TreatmentsBacillus and Francisella bacterial research