Litcius/Paper detail

Partial Scanning Transmission Electron Microscopy with Deep Learning

Jeffrey M. Ede, Richard Beanland

2020Scientific Reports45 citationsDOIOpen Access PDF

Abstract

Compressed sensing algorithms are used to decrease electron microscope scan time and electron beam exposure with minimal information loss. Following successful applications of deep learning to compressed sensing, we have developed a two-stage multiscale generative adversarial neural network to complete realistic 512 × 512 scanning transmission electron micrographs from spiral, jittered gridlike, and other partial scans. For spiral scans and mean squared error based pre-training, this enables electron beam coverage to be decreased by 17.9× with a 3.8% test set root mean squared intensity error, and by 87.0× with a 6.2% error. Our generator networks are trained on partial scans created from a new dataset of 16227 scanning transmission electron micrographs. High performance is achieved with adaptive learning rate clipping of loss spikes and an auxiliary trainer network. Our source code, new dataset, and pre-trained models are publicly available.

Topics & Concepts

Artificial intelligenceComputer scienceDeep learningMean squared errorConvolutional neural networkClipping (morphology)Generator (circuit theory)Artificial neural networkSpiral (railway)Scanning electron microscopePattern recognition (psychology)Transmission (telecommunications)Scanning transmission electron microscopyAlgorithmTransmission electron microscopySet (abstract data type)Computer visionTest setOpticsMaterials scienceDigital pattern generatorCompressed sensingImage processingTemplateConventional transmission electron microscopeCathode rayApproximation errorAdaptive learningBeam (structure)Energy filtered transmission electron microscopyImage (mathematics)Advanced Electron Microscopy Techniques and ApplicationsCCD and CMOS Imaging SensorsElectron and X-Ray Spectroscopy Techniques