Accurate protein structure prediction: what comes next?
Chaok Seok, Minkyung Baek, Martin Steinegger, Hahnbeom Park, Gyu Rie Lee, Jonghun Won
Abstract
Protein structure prediction has become extremely accurate, and its results are now comparable with those of experimental methods for a large number of proteins. However, there remain some technical hurdles to clear before the current structure prediction tools can be directly applied to a wide range of biomedical problems. New perspectives on future developments in the area of structure prediction and its biomedical applications are presented.
Topics & Concepts
Protein structure predictionComputer scienceRange (aeronautics)Data scienceProtein structureEngineeringBiologyAerospace engineeringBiochemistryProtein Structure and DynamicsEnzyme Structure and FunctionRNA and protein synthesis mechanisms