Tumor suppressive activity of miR-424-5p in breast cancer cells through targeting PD-L1 and modulating PTEN/PI3K/AKT/mTOR signaling pathway
Narges Dastmalchi, Mohammad Ali Hosseinpour Feizi, Seyed Mahdi Banan Khojasteh, Behzad Baradaran, Reza Safaralizadeh
Topics & Concepts
PTENPI3K/AKT/mTOR pathwayProtein kinase BCancer researchTransfectionViability assayCell growthAutophagymicroRNACell cycleBiologyApoptosisFlow cytometryCell biologySignal transductionCell cultureMolecular biologyGeneGeneticsBiochemistryMicroRNA in disease regulationCancer Immunotherapy and BiomarkersCancer Mechanisms and Therapy