Motility induced phase separation of deformable cells
Austin Hopkins, Benjamín Loewe, Michael Chiang, Davide Marenduzzo, M. Cristina Marchetti
Abstract
, squishy, cells phase separate more effectively than their rigid counterparts. This can be understood as due to the fact that deformability increases the effective duration of collisions. In addition, the dense regions become increasingly disordered as deformability increases. Our results contextualize the applicability of MIPS to biological systems and have implications for how cells in biological systems may self-organize.
Topics & Concepts
MotilityPhase (matter)StiffnessProxy (statistics)Biological systemMaterials scienceChemical physicsBiophysicsMechanicsChemistryPhysicsComputer scienceBiologyComposite materialCell biologyOrganic chemistryMachine learningMicro and Nano RoboticsCellular Mechanics and InteractionsMicrofluidic and Bio-sensing Technologies