Development and characterisation of novel poly (vinyl alcohol)/poly (vinyl pyrrolidone)-based hydrogel-forming microneedle arrays for enhanced and sustained transdermal delivery of methotrexate
Ismaiel A. Tekko, Gaoyun Chen, Juan Domínguez‐Robles, Raghu Raj Singh Thakur, Iman Hamdan, Lalitkumar K. Vora, Eneko Larrañeta, James C. McElnay, Helen O. McCarthy, Madeleine Rooney, Ryan F. Donnelly
Topics & Concepts
TransdermalVinyl alcoholMethotrexateEx vivoPharmacologyTransdermal patchChemistryIn vivoDrug deliveryBioavailabilityPharmacokineticsMedicineSurgeryIn vitroOrganic chemistryBiochemistryBiotechnologyPolymerBiologyAdvancements in Transdermal Drug DeliveryDermatology and Skin DiseasesToxin Mechanisms and Immunotoxins