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Mild diazenylation of C<sub>sp<sup>2</sup></sub>–H and C<sub>sp<sup>3</sup></sub>–H bonds <i>via</i> arylazo sulfones

Yulei Zhao, Shuai Cheng Li, Yuhang Fan, Chao Chen, Xiaotong Dong, Ruiqing Wang, Yuan‐Ye Jiang

2023Organic Chemistry Frontiers15 citationsDOI

Abstract

A transition-metal-free method to access non-symmetric azo derivatives via cross-couplings of arylazo sulfones with C sp 2 –H and C sp 3 –H is reported. The results presented herein shed light on the unconventional utilization of arylazo sulfones.

Topics & Concepts

ChemistryTransition metalMedicinal chemistryMetalStereochemistryOrganic chemistryCatalysisSulfur-Based Synthesis TechniquesRadical Photochemical ReactionsCatalytic C–H Functionalization Methods
Mild diazenylation of C<sub>sp<sup>2</sup></sub>–H and C<sub>sp<sup>3</sup></sub>–H bonds <i>via</i> arylazo sulfones | Litcius