Preparation and characterization of flexible furosemide-loaded biodegradable microneedles for intradermal drug delivery
Arsalan Abu‐Much, Raya Darawshi, Hala Dawud, Haytam Kasem, Aiman Abu Ammar
Abstract
, and will permit intradermal delivery of FUR. The MNs were further characterized by analytical methods. Finally, the MNs exhibited an initial burst release followed by a sustained release of FUR. Self-administered FUR-MNs can open new avenues to overcome i.v. drip limitations and increase patient compliance.
Topics & Concepts
PLGATransdermalDrug deliveryStratum corneumBiomedical engineeringBiocompatibilityDrugDosage formFurosemideControlled releaseMaterials sciencePharmacologyChemistryNanotechnologyMedicinePathologyNanoparticleMetallurgyOrganic chemistryAdvancements in Transdermal Drug DeliveryAdvanced Drug Delivery SystemsOcular Surface and Contact Lens