Cytotoxic Properties of 1,3,4-Thiadiazole Derivatives—A Review
Sara Janowska, Agata Paneth, Monika Wujec
Abstract
During recent years, small molecules containing five-member heterocyclic moieties have become the subject of considerable growing interest for designing new antitumor agents. One of them is 1,3,4-thiadiazole. This study is an attempt to collect the 1,3,4-thiadiazole and its derivatives, which can be considered as potential anticancer agents, reported in the literature in the last ten years.
Topics & Concepts
Combinatorial chemistryChemistryStereochemistrySynthesis and biological activitySynthesis and Characterization of Heterocyclic CompoundsQuinazolinone synthesis and applications