Single-nucleotide variants, tumour mutational burden and microsatellite instability in patients with metastatic colorectal cancer: Next-generation sequencing results of the FIRE-3 trial
Arndt Stahler, Sebastian Stintzing, Jobst C. von Einem, C. Benedikt Westphalen, Kathrin Heinrich, Nicole Krämer, Marlies Michl, Dominik Paul Modest, Ludwig Fischer von Weikersthal, Thomas Decker, Alexander Kiani, Tobias Heintges, Christoph Kahl, Frank Kullmann, Werner Scheithauer, Markus Moehler, Florian Kaiser, Thomas Kirchner, Andreas Jung, Volker Heinemann
Topics & Concepts
KRASMicrosatellite instabilityHazard ratioCetuximabInternal medicineColorectal cancerMedicineOncologyV600EOdds ratioPanitumumabConfidence intervalCancerCancer researchMutationMicrosatelliteBiologyGeneticsAlleleGeneColorectal Cancer Treatments and StudiesCancer Genomics and DiagnosticsGenetic factors in colorectal cancer