PINK1 insufficiency can be exploited as a specific target for drug combinations inducing mitochondrial pathology-mediated cell death in gastric adenocarcinoma
Sayak Ghosh, Debapriya Ghatak, R. K. Dutta, Devyani Goswami, Rudranil De
Topics & Concepts
DNM1LProgrammed cell deathApoptosisCancer cellMitochondrionCancer researchCancerPINK1MitophagyBiologyMitochondrial fissionDownregulation and upregulationCell biologyAutophagyBiochemistryGeneticsGeneAutophagy in Disease and TherapyMitochondrial Function and PathologyRNA modifications and cancer