Photocatalyst-free visible-light-induced highly selective acylation of purine nucleosides at the C6 position
Luohao Li, Huiqin Zheng, Feixiang Guo, Ze-hui Fang, Qianqian Sun, Jing Li, Qinghe Gao, Tao Zhang, Lizhen Fang
Abstract
A protocol for visible-light-induced C-H acylation selectively at the C6 position of purine nucleosides with aldehydes under photocatalyst-free conditions was established herein. This protocol allows the green, mild, and efficient functionalization of various purine nucleosides with a broad range of alkyl and aryl aldehydes.
Topics & Concepts
AcylationPurinePhotocatalysisChemistryVisible spectrumPhotochemistryPosition (finance)Combinatorial chemistryOrganic chemistryMaterials scienceCatalysisOptoelectronicsEnzymeEconomicsFinanceRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques