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Double knockout of Akt2 and AMPK accentuates high fat diet-induced cardiac anomalies through a cGAS-STING-mediated mechanism

Yan Gong, Guangwei Li, Jun Tao, Ne N. Wu, Machender R. Kandadi, Yaguang Bi, Shuyi Wang, Zhaohui Pei, Jun Ren

2020Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease66 citationsDOI

Topics & Concepts

EndocrinologyInternal medicineAMPKProtein kinase BCardiac function curveBiologyAKT2PhosphorylationProtein kinase AMedicineCell biologyHeart failureAKT1interferon and immune responsesRNA modifications and cancerCancer-related molecular mechanisms research
Double knockout of Akt2 and AMPK accentuates high fat diet-induced cardiac anomalies through a cGAS-STING-mediated mechanism | Litcius