Metal-free carbon monoxide-releasing micelles undergo tandem photochemical reactions for cutaneous wound healing
Jian Cheng, Bin Zheng, Sheng Cheng, Guoying Zhang, Jinming Hu
Abstract
as a result of the incorporation of 3-HF derivatives. More importantly, the localized CO delivery of CORPs by taking advantage of the spatiotemporal control of light stimulus outperformed conventional metal carbonyls such as CORMs in terms of anti-inflammation and cutaneous wound healing. This work opens a novel avenue toward metal-free CORPs for potential biomedical applications.
Topics & Concepts
Carbon monoxidePolymerizationMetalChemistryPhotochemistryPolymerWound healingTandemOrganic chemistryMaterials scienceSurgeryCatalysisMedicineComposite materialHeme Oxygenase-1 and Carbon MonoxideBurn Injury Management and OutcomesPhotodynamic Therapy Research Studies