Sinensetin attenuates IL-1β-induced cartilage damage and ameliorates osteoarthritis by regulating SERPINA3
Zhendong Liu, Ruizhou Liu, Rui Wang, Jihang Dai, Hui Chen, Jingcheng Wang, Xiaolei Li
Abstract
SIN, respectively. The knee cartilage tissue was removed 6 weeks after surgery for analysis and detection, and our studies have shown that SIN can effectively delay the progression of OA in rats and protect cartilage. In conclusion, our study shows that SIN has good application potential in the treatment of OA.
Topics & Concepts
OsteoarthritisPharmacologyChemistryMedicineInternal medicinePathologyAlternative medicineNatural product bioactivities and synthesisFlavonoids in Medical ResearchInflammatory mediators and NSAID effects