Multifunctional <scp>l</scp>-arginine-based magnetic nanoparticles for multiple-synergistic tumor therapy
Haiyan Yang, Fujie Jiang, Liang Zhang, Lu Wang, Yong Luo, Ningshan Li, Yu Guo, Qi Wang, Jianzhong Zou
Abstract
to produce highly reactive oxygen-containing species (ROS) to accelerate the oxidation of LA and the release of NO. This novel strategy showed synergistic tumor growth suppression as compared with individual HIFU therapy or gas therapy. This can be attributed to the rational design of multifunctional NPs with magnetic targeting and multi-modality imaging properties.
Topics & Concepts
ChemistryArginineNanoparticleMagnetic nanoparticlesBiophysicsBiochemistryCell biologyNanotechnologyAmino acidBiologyMaterials scienceNanoplatforms for cancer theranosticsNanoparticle-Based Drug DeliveryAdvanced biosensing and bioanalysis techniques