Mechanosensitive Piezo1 channel activation promotes ventilator-induced lung injury via disruption of endothelial junctions in ARDS rats
Lulu Jiang, Yang Zhang, Dahao Lu, Tianfeng Huang, Keshi Yan, Wenjun Yang, Ju Gao
Topics & Concepts
PIEZO1ARDSAdherens junctionCalpainLungLipopolysaccharideChemistryMedicineMechanosensitive channelsCell biologyInternal medicineBiologyIon channelCellCadherinBiochemistryEnzymeReceptorErythrocyte Function and PathophysiologyHeme Oxygenase-1 and Carbon MonoxideThermoregulation and physiological responses