Dose-dependent pleiotropic role of neutrophils during acetaminophen-induced liver injury in male and female mice
Nga Nguyen, David S. Umbaugh, Sawyer Smith, Olamide B. Adelusi, Giselle Sánchez-Guerrero, Anup Ramachandran, Hartmut Jaeschke
Topics & Concepts
Liver injuryAcetaminophenMedicineNecrosisCXCL2Infiltration (HVAC)Internal medicinePharmacologyMonocyteNeutrophileImmunologyInflammationChemokineEndocrinologyPhysicsChemokine receptorThermodynamicsDrug-Induced Hepatotoxicity and ProtectionImmune Response and InflammationPharmacogenetics and Drug Metabolism