Comorbidity and comedication burden among people living with HIV in the United States
Misti L. Paudel, Girish Prajapati, Erin Buysman, Swarnali Goswami, Jianbin Mao, Kimberly McNiff, Princy Kumar
Abstract
OBJECTIVE: To describe the burden of comorbid conditions and comedications among people living with HIV (PLWH) vs. people living without HIV (PLWoH). METHODS: -tests with robust standard errors in an ordinary least squares regression or Rao-Scott tests. RESULTS: < .001). CONCLUSIONS: Multimorbidity and polypharmacy were more prevalent among PLWH vs. matched PLWoH. Findings support the need to consider comorbidities and comedications when choosing ART and to minimize drug-drug interactions and adverse events to improve patient outcomes.
Topics & Concepts
MedicineComorbidityInternal medicineDepression (economics)Medical prescriptionCharlson comorbidity indexDiabetes mellitusHuman immunodeficiency virus (HIV)DemographyImmunologyEconomicsEndocrinologyPharmacologySociologyMacroeconomicsHIV-related health complications and treatmentsHIV/AIDS Research and InterventionsPneumocystis jirovecii pneumonia detection and treatment