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Lymph node macrophages drive immune tolerance and resistance to cancer therapy by induction of the immune-regulatory cytokine IL-33

Sara Lamorte, Rene Quevedo, Robbie Jin, Luke Neufeld, Zhe Qi Liu, Marion Ciudad, Sabelo Lukhele, Jessica Bruce, Shreya Mishra, Xin Zhang, Zaid Kamil Saeed, Hal K. Berman, Dana J. Philpott, Stephen E. Girardin, Shane M. Harding, David H. Munn, Tak W. Mak, Mikael C. I. Karlsson, David G. Brooks, Tracy L. McGaha

2025Cancer Cell32 citationsDOIOpen Access PDF

Topics & Concepts

Immune systemCytokineImmunologyLymph nodeImmune toleranceCancerImmunityCancer researchBiologyMedicineGeneticsIL-33, ST2, and ILC PathwaysImmune Cell Function and InteractionCancer Immunotherapy and Biomarkers
Lymph node macrophages drive immune tolerance and resistance to cancer therapy by induction of the immune-regulatory cytokine IL-33 | Litcius