Protective effects of berberine against MPTP-induced dopaminergic neuron injury through promoting autophagy in mice
Han Deng, Zegang Ma
Abstract
Berberine protects dopaminergic neurons in SN of MPTP-induced mice via the enhancement of AMPK-mediated autophagy.
Topics & Concepts
BerberineMPTPAMPKCoptis chinensisSubstantia nigraAutophagyAlkaloidPharmacologyPars compactaChemistryDopaminergicProtein kinase ADopamineBiochemistryBiologyEndocrinologyMedicineKinaseApoptosisStereochemistryAlternative medicineTraditional Chinese medicinePathologyAutophagy in Disease and TherapyParkinson's Disease Mechanisms and TreatmentsCannabis and Cannabinoid Research