A dimer-monomer switch controls CHIP-dependent substrate ubiquitylation and processing
Vishnu Balaji, Leonie Müller, Robin Lorenz, Éva Kevei, William Zhang, Ulises Santiago, Jan M. Gebauer, Ernesto Llamas, David Vı́lchez, Carlos J. Camacho, Wojciech Pokrzywa, Thorsten Hoppe
Topics & Concepts
Ubiquitin ligaseUbiquitin-Protein LigasesUbiquitinBiologyChaperone (clinical)Cell biologyBiophysicsProteasomeCaenorhabditis elegansHsp90ParkinBiochemistryHeat shock proteinGeneParkinson's diseasePathologyMedicineDiseaseUbiquitin and proteasome pathwaysGenetics, Aging, and Longevity in Model OrganismsEndoplasmic Reticulum Stress and Disease