NF-κB pathway affects silica nanoparticle-induced fibrosis via inhibited inflammatory response and epithelial-mesenchymal transition in 3D co-culture
Xiaojing Yang, Jing Zhang, Min Xiong, Yushan Yang, Yang Pan, Ning Li, Fan Shi, Yaxin Zhu, Keyun Guo, Yulan Jin
Topics & Concepts
MatrigelEpithelial–mesenchymal transitionDownregulation and upregulationMesenchymal stem cellFibronectinMyofibroblastTumor necrosis factor alphaCell biologyCell cultureChemistryCancer researchA549 cellFibrosisNF-κBCellInflammationBiologyImmunologyPathologyMedicineExtracellular matrixAngiogenesisBiochemistryGeneticsGeneOccupational and environmental lung diseasesCancer Cells and MetastasisCancer Research and Treatments