Nano-designed carbon monoxide donor SMA/CORM2 exhibits protective effect against acetaminophen induced liver injury through macrophage reprograming and promoting liver regeneration
Bingdong Song, Cheng Zhang, Weirong Hu, Chunyu Guo, Zhengmei Xia, Wanxia Hu, Ming-Qiang Qin, Weiying Jiang, Jin-Wei Lv, De‐Xiang Xu, Shichen Zhang, Jun Fang
Topics & Concepts
Liver injuryChemistryMacrophage polarizationProtein kinase BPI3K/AKT/mTOR pathwayProinflammatory cytokinePharmacologyReactive oxygen speciesLiver regenerationReperfusion injuryCytoprotectionInflammationCancer researchOxidative stressBiochemistryCell biologySignal transductionMedicineMacrophageImmunologyInternal medicineBiologyIschemiaRegeneration (biology)In vitroHeme Oxygenase-1 and Carbon MonoxideAlcohol Consumption and Health EffectsThermal Regulation in Medicine