An electrochemical biosensor for PD-L1 positive exosomes based on ultra-thin two-dimensional covalent organic framework nanosheets coupled with CRISPR-Cas12a mediated signal amplification
Minghui Wang, Yuxin Lin, Shuai Wu, Ying Deng, Yuanyuan Zhang, Jie Yang, Genxi Li
Topics & Concepts
MicrovesiclesCRISPRMaterials scienceBiosensorDetection limitNanotechnologyAptamerElectrodeExosomeColloidal goldCovalent bondLinear rangeRolling circle replicationElectrochemistryNanoparticleChemistryMolecular biologyBiologymicroRNAChromatographyDNABiochemistryGeneOrganic chemistryDNA replicationPhysical chemistryAdvanced biosensing and bioanalysis techniquesMXene and MAX Phase MaterialsNanopore and Nanochannel Transport Studies