Alterations of gut microbiome in patients with type 2 diabetes mellitus who had undergone cholecystectomy
Bin Wei, Yakun Wang, Shoukui Xiang, Yan Jiang, Rong Chen, Nan Hu
Abstract
The gut microbiome of long-term T2DM patients who had undergone cholecystectomy and age- and/or sex-matched subjects of new-onset and long-term T2DM without cholecystectomy was assessed using 16S rRNA gene sequencing in stool samples. The findings suggest that, cholecystectomy could partially alleviate long-term diabetes-induced dysbiosis of gut microbiome composition and function.
Topics & Concepts
CholecystectomyMicrobiomeDysbiosisGut microbiomeDiabetes mellitusGut floraMedicineType 2 diabetesType 2 Diabetes MellitusGastroenterologyInternal medicineBiologyBioinformaticsImmunologyEndocrinologyGut microbiota and healthGastrointestinal motility and disordersHelicobacter pylori-related gastroenterology studies