CRISPR-mediated Sox9 activation and RelA inhibition enhance cell therapy for osteoarthritis
Lan Zhao, Yumei Lai, Hongli Jiao, Jun Li, Ke Lu, Jian Huang
Topics & Concepts
Mesenchymal stem cellOsteoarthritisChondrogenesisCRISPRCartilageCell therapyGenetic enhancementImmune systemSOX9Cancer researchMedicineStromal cellCell biologyChemistryImmunologyBiologyGene expressionStem cellPathologyGeneAnatomyBiochemistryAlternative medicineOsteoarthritis Treatment and MechanismsRNA Interference and Gene DeliveryCAR-T cell therapy research