Skin-like wound dressings with on-demand administration based on<i>in situ</i>peptide self-assembly for skin regeneration
Xiaoying Zhang, Cong Liu, Pengsheng Fan, Xuehao Zhang, Da‐Yong Hou, Jiaqi Wang, Hui Yang, Hao Wang, Zeng‐Ying Qiao
Abstract
self-assembly of peptides and the resultant high-efficiency sterilization. Compared with the commercial antibacterial dressing, the SF-GPLK displayed a faster wound healing rate. When a skin wound is not infected, the GPLK peptides remain in the SF, realizing good biosafety. Generally, the EGF can be released to promote wound healing and skin regeneration in both cases. Therefore, skin-like SF-GPLK wound dressings with on-demand release of antibacterial peptides provide a smart administration mode for clinical wound management and skin regeneration.
Topics & Concepts
Regeneration (biology)In situPeptideWound healingMaterials scienceBiomedical engineeringMedicineSurgeryCell biologyChemistryBiochemistryBiologyOrganic chemistrySilk-based biomaterials and applicationsPolymer Surface Interaction StudiesAntimicrobial Peptides and Activities