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Human-AI Interaction in the ScreenTrustCAD Trial: Recall Proportion and Positive Predictive Value Related to Screening Mammograms Flagged by AI CAD versus a Human Reader

Karin Dembrower, Alessio Crippa, Martin Eklund, Fredrik Strand

2025Radiology13 citationsDOI

Abstract

< .001). For examinations flagged by all three readers, the proportion recalled was 82.6% (400 of 484) and the PPV was 34.2 (137 of 400). Conclusion A larger proportion of participants were recalled after initial flagging by radiologists compared with those flagged by AI CAD, with a lower proportion of cancer. ClinicalTrials.gov Identifier: NCT04778670 © RSNA, 2025 See also the editorial by Grimm in this issue.

Topics & Concepts

MedicineMammographyPredictive valueRecallBreast cancerDigital mammographyValue (mathematics)Screening mammographyMedical physicsGynecologyCancerInternal medicineStatisticsMathematicsPhilosophyLinguisticsArtificial Intelligence in Healthcare and EducationAI in cancer detectionRadiomics and Machine Learning in Medical Imaging
Human-AI Interaction in the ScreenTrustCAD Trial: Recall Proportion and Positive Predictive Value Related to Screening Mammograms Flagged by AI CAD versus a Human Reader | Litcius