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Mathematical and numerical analysis of a fractional SIQR epidemic model with normalized Caputo–Fabrizio operator and machine learning approaches

Ramsha Shafqat, Ateq Alsaadi

2025AIMS Mathematics10 citationsDOIOpen Access PDF

Abstract

This paper introduces, analyzes, and numerically investigates a fractional-order SIQR epidemic model with the normalized Caputo–Fabrizio derivative. The model captures memory effects and the impact of quarantine or isolation interventions, offering a more realistic description of epidemic dynamics. We establish the existence, uniqueness, positivity, and population conservation properties, and then propose a robust numerical scheme. The influence of the memory parameter and kernel normalization is illustrated via simulations, with a discussion on their implications for epidemic forecasting and real-world control strategies. Furthermore, artificial neural networks are applied, with the dataset partitioned into training, validation, and testing subsets. A comprehensive assessment is carried out for each dataset partition.

Topics & Concepts

Operator (biology)Applied mathematicsMathematicsFractional calculusComputer scienceCalculus (dental)MedicineBiologyGeneDentistryRepressorBiochemistryTranscription factorFractional Differential Equations SolutionsMathematical and Theoretical Epidemiology and Ecology ModelsCOVID-19 epidemiological studies
Mathematical and numerical analysis of a fractional SIQR epidemic model with normalized Caputo–Fabrizio operator and machine learning approaches | Litcius