Catalytic enantioselective construction of vicinal quaternary carbon stereocenters
Feng Zhou, Lei Zhu, Bo‐Wen Pan, Yang Shi, Yun‐Lin Liu, Jian Zhou
Abstract
This review summarizes the advances in the catalytic enantioselective construction of vicinal quaternary carbon stereocenters, introduces major synthetic strategies and discusses their advantages and limitations, highlights the application of known protocols in the total synthesis of natural products, and outlines the synthetic opportunities.
Topics & Concepts
StereocenterEnantioselective synthesisVicinalCatalysisQuaternary carbonCarbon fibersCombinatorial chemistryChemistryOrganic chemistryComputer scienceAlgorithmComposite numberAsymmetric Synthesis and CatalysisAsymmetric Hydrogenation and CatalysisSynthetic Organic Chemistry Methods